Research
Laith Mukdad has worked on a project examining the efficacy of screen-based simulation in assessing medical student knowledge of shock. Using programming tools, CORE Lab has developed a screen-based simulator, integrating fundamental hemodynamic parameters and electrocardiography to mimic the data-rich environment of the ICU. Laith then used this simulator as a teaching tool in a randomized trial with 56 second-year UCLA medical students, presenting them six patient-based scenarios, consisting of different forms of shock. This trial demonstrated the superiority of the simulator to conventional didactics in assessing clinical competency. Today, he aims to implement larger studies to further evaluate the simulator's efficacy as an assessment tool at different levels of training.
Rustin Kashani is researching clinical parameters that may predict post-operative atrial fibrillation. He is also investigating the utility of surface EKGs in determining freedom from atrial fibrillation after catheter ablation.
Extracorporeal membrane oxygenation (ECMO) has been used to support patients with advanced cardiac and/or pulmonary failure. More recently, venoarterial (VA) ECMO has been used as an adjunct to CPR, which has increased the number of patients on extracorporeal support. With an increase in ECMO utilization worldwide and the need for a cost efficient healthcare system, Eric Pillado's present study aims to evaluate patient outcomes and hospital costs at UCLA Health.
Imani McElroy is currently working on modifying protocols for readmission reduction programs at our institution in hopes of lowering readmissions rates of cardiac surgery patients. She hopes her research can also be used to reduce the disparity gap for underserved patients.
Son Nguyen is currently looking at potential risk factors that may predict post-operative dysphagia. He hopes to find potential intervention to prevent post-operative dysphagia. He is also currently working with the transcranial doppler machine to show that internal carotid artery clamping during pivotal times during cardiac surgery can help reduce the emboli traveling to the patient's brain.
Adeel Ashfaq is currently evaluating ARI data from post-operative patient EKGs to determine its efficacy as a predictor for atrial fibrillation after cardiac surgery. Additionally, he is analyzing ARI data from pig experiments to elucidate how ARIs may change under different experimental manipulations.
Ryan Ou is researching myocardial protection offered by different cardioplegia methods and clinical outcomes such as atrial fibrillation rates. He is also looking at septal dyskinesia and relation to operative approach.
Allen Zhu is developing and investigating a light-based bubble detection system for use with chest tube drainage systems to quantify and analyze the presence of air leaks.
Sohail Sareh: Since 2012, Sohail Sareh has been involved in a number of projects focused on the perioperative management of surgical patients, postoperative outcomes of cardiac patients, as well as medical education. His work on predicting postoperative atrial fibrillation, and the risks and benefits of perioperative Beta blocker and Statin use, has been presented at national meetings, and has led to multiple publications in peer-reviewed journals. His current focus is on the utility of perioperative transfusions in surgical patients.
Publications:
Kashani R, Bowles C, Sareh S, Toppen W, Ou R, Shemin R, Benharash P. Use of preoperative aspirin in combined coronary and valve operations. Surgery. 2016 Aug 30. doi: 10.1016/j.surg.2016.07.034.
McElroy I, Sareh S, Zhu A, Miranda G, Wu H, Nguyen M, Shemin R, Benharash P. Use of digital health kits to reduce readmission after cardiac surgery. J Surg Res. 2016 Jul. 204(1): 1-7. doi: 10.1016/j.jss.2016.04.028.
Ashfaq A, Zhu A, Iyengar A, Wu H, Humphries R, McKinnell JA, Shemin R, Benharash P. Impact of an institutional antimicrobial stewardship program on bacteriology of surgical site infections in cardiac surgery. J Card Surg. 2016 Jun. 31(6): 367-72. doi: 10.1111/jocs.12756.
Santhanam AP, Neylon J, Eldredge J, Teran J, Dutson E, Benharash P. GPU-based parallelized solver for large scale vascular blood flow modeling and simulations. Stud Health Technol Inform. 2016. 220: 345-51.
Toppen W, Sareh S, Johansen D, Genovese B, Satou N, Shemin R, Benharash P. Addition of statins to treatment with β-blockers to improve outcomes for cardiac surgery patients: beyond the surgical care improvement project. JAMA Surg. 2015 Nov 18. doi: 10.1001/jamasurg.2015.4212.
Buch E, Share M, Tung R, Benharash P, Sharma P, Koneru J, Mandapati R, Ellenbogen KA, Shivkumar K.Long-term clinical outcomes of focal impulse and rotor modulation for treatment of atrial fibrillation: A multicenter experience. Heart Rhythm. 2015 Oct 21. pii: S1547-5271(15)01314-4. doi: 10.1016/j.hrthm.2015.10.031.
Benharash P, Buch E, Frank P, Share M, Tung R, Shivkumar K, Mandapti R.Quantitative analysis of Localized sources identified by focal impulse and rotor modulation mapping in atrial fibrillation. Circ Arrythm Electrophysiol. 2015 June;8(3):554-61. doi:10.1161/CIRCEP.115.002721
Kashani R, Sarah S, Genovese B, Hershey C, Rezentes C, Shemin R, Buch E, Benharash P.Predicting postoperative atrial fibrillation using CHA2DS2VASc scores. J Surg Res. 2015 Apr 18. Pii: S0022-4804-1. doi: 10.1016/j.jss.2015.04.047
Gee E, Lancester E, Meltzer, Mendelsohn AH, Benharash P. A targeted swallow screen for the detection of postoperative dysphagia. Am Surg. 2015 Oct; 81(10):970-82
Zhou W, Benharash P, Han Chua J, Nakahara S, Ho JK, Mahajan A. Acute effects of pacing at different ventricular sites on left ventricular rotational mechanics in a porcine model. J Cardiothorac Vasc Anesth. 2014 Dec 8. Pii: s1053-0770(14) 00608-9. doi: 10.1053/j.jvc a.2014.12.2008
Sareh S, Toppen W, Mukdad L, Satou N, Shemin R, Buch E, Benharash P.CHADS2 score predicts atrial fibrillation following cardiac surgery.J Surg Res. 2014 Aug;190(2):407-12. doi: 10.1016/j.jss.2014.02.007
Toppen W, Sareh S, Satou N, Shemin R, Hunter C, Buch E, Benharash P. β-blockers improve postoperative outcomes in patients undergoing cardiac surgery? Challenging societal guidelines. Am Surg. 2014 Oct;80(10):1018-21.
Postel P, Frank PN, Barry T, Satou N, Shemin R, Benharash P.The cost of preventing readmissions: why surgeons should lead the effort. Am Surg. 2014 Oct;80(10):1003-6.
Zhou W, Benharash P.Effects and mechanisms of acupuncture based on the principle of meridians.J Acupunct Meridian Stud. 2014 Aug;7(4):190-3. doi: 10.1016/j.jams.2014.02.007
Zhou W, Benharash P.Significance of "Deqi" response in acupuncture treatment: myth or reality.J Acupunct Meridian Stud. 2014 Aug;7(4):186-9. doi: 10.1016/j.jams.2014.02.008
Lancaster E, Postel M, Satou N, Shemin R, Benharash P.Introspection into institutional database allows for focused quality improvement plan in cardiac surgery: example for a new global healthcare system.Am Surg. 2013 Oct;79(10):1040-4
Benharash P, Frank PN, Hoy B. Development and use of a novel cardiovascular simulator: time for a paradigm shift? American Surgeon (2012) 78.10:1132-1136
